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AOPs / Publications

AOP chapter in newly published “Encyclopedia of Toxicology”

“Adverse Outcome Pathways: Development and Use in Toxicology,” a chapter in Elsevier’s Encyclopedia of Toxicology (3rd edition) written by HSUS/HTPC’s Dr. Catherine Willett, introduces readers to the concept of Adverse Outcome Pathways (AOP) and explains how they can improve the efficiency and accuracy of toxicity testing while reducing the use of animals.  Dr. Willett’s chapter … Continue reading

AOPs / Meetings & Events

Successful “AOPs 101″ ancillary workshop at SOT 2014

“AOPs 101: the How and Why of Development and Use,” the ancillary program co-sponsored and organized by HTPC and ASCCT, was a perfect fit for this year’s SOT conference.  With an unprecedented number of Adverse Outcome Pathway (AOP)-related sessions and symposia on the 2014 Scientific Program, the workshop’s aim to introduce AOP fundamentals to scientists … Continue reading

AOPs / Meetings & Events / Publications

HTPC liver toxicity workshop proceedings published in ALTEX, “Online First”

“Building Shared Experience to Advance Practical Application of Pathway-Based Toxicology:Liver Toxicity Mode-of-Action,” a report summarizing a workshop coordinated by HTPC in 2013, and co-authored by workshop participants, has been published by ALTEX in “Online First.”  From the summary: A workshop sponsored by the Human Toxicology Project Consortium (HTPC), “Building Shared Experience to Advance Practical Application … Continue reading

AOPs / Meetings & Events

“Advancing AOPs for Integrated Toxicology and Regulatory Applications”

Human Toxicology Project Consortium Coordinator Catherine Willett was in Italy last week to take part in “Advancing AOPs for Integrated Toxicology and Regulatory Applications.”  Co-sponsored by a broad range of stakeholders*  and organized by the European Commission, US Army Corps and US EPA, this workshop was designed to build on the advancements of two previous … Continue reading

TSCA

Consortium Coordinator Catherine Willett testifies on chemical legislation

Dr. Catherine Willett, HSUS Director of Regulatory Toxicology, Risk Assessment, and Alternatives, and coordinator of the Human Toxicology Project Consortium, testified Tuesday before the US House of Representatives Energy and Commerce Subcommittee on Environment and the Economy, on the testing and reporting requirements included in the Toxic Substances Control Act (TSCA).  The subcommittee has been … Continue reading

AOPs / Meetings & Events

SOT Ancillary Workshops on Adverse Outcome Pathways

The HTPC and the American Society for Cellular and Computational Toxicology are coordinating two Ancillary Workshops on Adverse Outcome Pathways at the Society of Toxicology’s Annual Meeting in Phoenix, Arizona. “AOPs 101: The How and Why of Development and Use” will compliment several presentations on Adverse Outcome Pathways at the SOT meeting, and is intended … Continue reading