The Human Toxicology Project Consortium will once again co-sponsor an Adverse Outcome Pathway-training at the Society of Toxicology’s (SOT) annual meeting in Baltimore, Maryland. On Tuesday, March 14, from 5:00PM-7:00PM, registrants can take part in our Hands-On Seminar: Creating an Adverse Outcome Pathway in the AOP Wiki, which HTPC is co-sponsoring with the Physicians Committee for Responsible Medicine (PCRM).

At this seminar, participants will have a chance to deepen their understanding of the AOP Wiki (Version 2.0) and gain experience entering an Adverse Outcome Pathway.  Attendees will work through a case example in small groups.  In addition, participants will get a preview of an online course on AOPs and the AOP-Wiki that will soon be available here on the HTPC website.

Agenda:

5:00-5:20: International Efforts to Identify, Standardize, and Apply AOPs (Kristie Sullivan, PCRM)

5:20-6:00: A New Online Course on Adverse Outcome Pathways (Catherine Willett, HTPC)

6:00-7:00: The AOP Wiki 2.0: Demonstration and hands-on exercise (Stephen Edwards, US EPA)

The seminar will take place in the Constellation Ballroom A – Hyatt Regency Baltimore, 300 Light Street.  Please register in advance with Kristie Sullivan at PCRM: ksullivan@pcrm.org

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At this SOT gathering, HTPC is also once again co-sponsoring (along with the Center for Alternatives to Animal Testing [CAAT] and the Human Toxome Project) the well-regarded satellite meeting, Updates on Activities Related to 21st Century Toxicology and Related Efforts.  As always, the meeting will feature a number of invited presentations, but also leave time for an “open microphone” segment in which participants are welcome to give brief presentations on germane topics, with or without a few slides.  This satellite meeting takes place Thursday, March 16 from noon to 4:30PM at the Lord Baltimore Hotel.

The draft program is as follows:

12:30 Box lunch (for pre-registered participants) and welcome, Thomas Hartung (Johns Hopkins University)

13:00 Invited speakers (10 minute presentations each followed by 5 mins. of discussion)

  • ToxCast Update – Russell Thomas (US Environmental Protection Agency)
  • EDSP21 Update – Stanley Barone (US Environmental Protection Agency)
  • Tox21 Update – Richard Paules (US National Toxicology Program)
  • TT21C update – Rebecca Clewell (ScitoVision)
  • NICEATM Update – Nicole Kleinstreuer (NICEATM)
  • EU Tox-Risk Update – Robert van de Water (University of Tuebingen)
  • NAS Report on Using 21st Century Science to Improve Risk-Related Evaluations – TBD
  • Evidence-based Toxicology Update – Katya Tsaioun (EBT Johns Hopkins)
  • CAAT’s Read-across Initiative and Human Toxome-related Activity Update – Thomas Hartung (Johns Hopkins)
  • Human Toxicology Project Consortium Update – Catherine Willett (HTPC)

15:15 Open microphone for additional presentations and discussion

16:00 Adjourn

Box lunches will be available to those who have pre-registered. Contact Jamie DeRita.

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Also at this year’s SOT meeting, HTPC coordinator Catherine Willett will present a poster on HTPC’s soon-to-be-released online training course on adverse outcome pathways. Look for her poster, “Advancing the Development of Quality AOPs Submitted to OECD’s AOP Knowledge Base (AOP-KB) and the AOP-Wiki” during the Late Breaking Poster Session on Thursday, March 16, from 9:00AM to noon (late-breaking abstract #3441; Poster # P413).