In 2014, the HTPC co-sponsored with the Physicians Committee for Responsible Medicine two introductory Adverse Outcome Pathway workshops, one at the Society of Toxicology annual meeting in Phoenix, Arizona, and the other at the World Congress on Alternatives and Animal Use in the Life Sciences, in Prague, Czech Republic. The workshops introduced the fundamentals of AOP construction and application to scientists interested in using AOPs in their own work, or interested in joining ongoing AOP projects. Plans are underway to create a webinar version of this well-received series. In the meantime, presentation slides are available below.
Society of Toxicology AOPs 101 Ancillary Workshop talks, March 25, 2014:
- Kristie Sullivan – What are AOPs?
- Catherine Willett – Why are AOPs important, and how can they be useful?
- Terry Schultz – AOPs: Getting Started
- Nicole Kleinstreuer – Constructing AOPs for Developmental Toxicities
- Grace Patlewicz – Development of an AOP for Skin Sensitization and Practical Applications (slides here)
- Mathieu Vinkin – Development and Use of Hepatic AOPs in the SEURAT Project Cluster
World Congress on Alternatives and Animal Use in the Life Sciences AOPs 101 Workshop talks, August 24, 2014:
- Catherine Willett, HSUS/HTPC – Why are AOPs important, and how can they be useful?
- Anne Gourmelon, OECD – The OECD program on AOPs
- Kristie Sullivan, PCRM – Practical experience using the AOP Wiki
- Hristo Aladjov, OECD – Introduction to Effectopedia
- Joanna Jaworska, P&G – Application of AOP in the Bayesian network ITS framework to assess skin sensitization
- Nicole Kleinstreuer, ILS/NICEATM – Constructing AOPs for Developmental Toxicities