Advancing a New Paradigm for Assessing Chemical Safety

The Human Toxicology Project Consortium (HTPC) is a multi-stakeholder coalition dedicated to accelerating the global implementation of a new paradigm in toxicity testing. Grounded in a mechanistic understanding of chemical-biological interactions, this systems-based approach will generate better data more efficiently on the potential risks of chemicals to humans and the environment. With more and better data comes the promise of improved risk-based regulatory decisions and greater public confidence in those decisions.

Advancing and Implementing the Science:

Consortium members and partners are working together to accelerate technical and scientific advances in pathway-based approaches to chemical safety assessment.

Communicating the Vision:

Communicating the purpose and goals of pathway-based approaches to understanding toxicity and disease is essential to building confidence in chemical and drug safety. Effective communication facilitates consensus building among stakeholders – including regulatory agencies, health officials and providers, consumers, and advocates for environmental and animal protection.

Advocacy:

To encourage research and development and speed its implementation, the Consortium works to effect policy changes and cultivate direct and indirect funding opportunities that support pathway-based approaches in the U.S. and internationally.

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