Join us at our SOT satellite meeting for the latest updates on 21st century toxicology

Attending the the Society of Toxicology’s annual meeting this March? Join the Human Toxicology Project Consortium (HTPC) and the Center for Alternatives to Animal Testing (CAAT) at our annual satellite meeting on advancing 21st century toxicology activities. The meeting provides an informal setting for interested stakeholders to update one other on this important topic. A number of invited presentations are featured; there will also be time for an “open microphone” segment in which participants are welcome to make announcements or to comment on germane topics, with or without a few slides.

Updates on Activities Related to 21st Century Toxicology:
Invited Presentations and Open Microphone
Thursday, March 14, 2019, 12:30-4:00 pm
Hilton Baltimore Hotel, Baltimore, MD

Registration

Please register by email at your earliest convenience with Camila Januario at cjanuar1@jhu.edu. Box lunches will be available to those who have pre-registered.

Agenda

12:30  Welcome – Martin Stephens (Johns Hopkins University); Box lunch (for pre-registered participants)

1:00    Invited updates (10-minute talks each followed by up to 5 minutes of discussion)

  • ToxCast – Russell Thomas (EPA)
  • Tox21 – Rick Paules (NIEHS)
  • EU Tox-Risk – Bob van de Water (Leiden University)
  • ICCVAM – Nicole Kleinstreuer (NICEATM)
  • Organ-on-a-chip & Predictive Toxicology Roadmap – Suzanne Fitzpatrick (FDA)
  • Progress in implementing NAMs under TSCA – Gino Scarano (EPA)
  • Canadian Centre for Alternatives to Animal Methods – Charu Chandrasekera (University of Windsor)
  • Evidence-based data analytics predict human DILI using ToxCast data – Katya Tsaioun (Johns Hopkins)
  • Human Toxicology Project Consortium – Catherine Willett (Humane Society International)
  • CAAT’s In Silico Prediction Tool – Thomas Hartung (Johns Hopkins)

3:30    Open microphone for comments, announcements, and discussion

4:00    Adjourn

CAAT HTPC partners organs-on-chips Tox21 ToxCast

Beyond Science and Decisions: From Problem Formulation to Dose-Response Assessment

The next workshop in the “Beyond Science and Decisions” series, “Beyond Science and Decisions: From Problem Formulation to Dose-Response Assessment,” will take place February 26 and 27, 2019, at the offices of Texas Commission on Environmental Quality in Austin, Texas. The “Beyond Science and Decisions” workshop series continues and expands upon the discussion set forth by Science and Decisions: Advancement of Risk Assessment (NAS, 2009).

The workshop agenda can be found here: https://tera.org/Alliance%20for%20Risk/TCE2018/Beyond_Science2018_Agenda.pdf. The agenda will include several case studies and multiple talks across a variety of topics.

Registration is free and can be found at: https://tera.org/Alliance%20for%20Risk/Workshop/WS10Registration.html. A block of hotel rooms is being reserved at the HILTON GARDEN INN AUSTIN NORTH. Information about these accommodations will be on the registration website shortly.

Meetings & Events

Symposium to discuss global harmonization of vaccine testing requirements

Human Toxicology Project Consortium partner Humane Society International will present a symposium on Global Harmonization of Vaccine Testing on March 19, 2019, in Rome. This event will bring together experts to discuss the elimination of abnormal toxicity tests and target animal batch safety tests for batch release of biologicals and immunologicals for human and veterinary use, a milestone that has been achieved in some regions. A key goal of the symposium is to explore barriers faced in regions still using these tests and what kind of actions should be taken or suggested to achieve elimination of these tests worldwide. A detailed overview of the symposium is available here. For more information, contact Laura Viviani at lviviani@hsi.org.

HSI HTPC partners vaccine testing

Unilever & Humane Society International join forces to end cosmetics animal testing

Human Toxicology Project Consortium founding members Unilever and Humane Society International (HSI) have teamed up to eliminate animal testing in the global cosmetics industry within five years.

Unilever has long been a leader in the development of non-animal toxicity test methods and strategies. Now the personal care giant has pledged support for HSI’s #BeCrueltyFree campaign and will work closely with HSI to advance policy changes that effectively ban cosmetics animal testing globally. For example, Unilever will back HSI’s efforts to strengthen Australia’s proposed cosmetics animal testing ban, bringing it into alignment with the complete ban already in place in the EU.

The two organizations will also collaborate with manufacturers and regulatory agencies to increase the use of non-test strategies for risk assessment. HSI’s Hannah Stuart, campaign manager for #BeCrueltyFree Australia, notes that a “combination of hazard-focused ‘Tox21‘ and exposure led ‘Risk21‘ approaches represents the future of safety assessment.”

Finally, to increase acceptance of non-animal test methods and non-test strategies across stakeholders – from consumers to regulators – the Unilever and HSI partnership will develop online training components (such as a Coursera course) that use real-world examples and case studies to teach users how these non-animal test and non-test strategies are applied in safety decisions about cosmetics ingredients.

Read more in Cosmetics Design Europe.

alternative toxicity testing cosmetics Humane Society International Tox21 Unilever

Introducing BioMed21.org

We’re excited to tell you about a brand-new initiative that we are involved in: the Biomedical Research for the 21st Century (BioMed21) Collaboration.

BioMed21 brings together scientists and institutions from across Europe, Asia and the Americas who share a vision of a human-focused paradigm in health research. This unique mix of biomedical stakeholders provides both a broad, global outlook as well as deep ties at regional and national levels.

The new BioMed21 website was designed to be a hub for information related to innovative, human-specific approaches in health research, including relevant publications, funding opportunities, workshops, training opportunities, and other events.

The newsletter delivers top highlights to your inbox every quarter.

Follow BioMed21 Twitter for more frequent updates.

On behalf of the Human Toxicology Project Consortium team, we look forward welcoming you to the BioMed21 online community!

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